However, compared to JAK2 positive patients with MPN, patients with JAK2 wild type had no statistically significant difference in white blood cell count, hemoglobin level, platelet count, PT, APTT, FIB, D-Dimer, ATIII, INR, etc. (P > 0.05) (Table 4). The gene discussed is SERPINC1; the disease is myeloproliferative neoplasm.