TNF and juvenile idiopathic arthritis: The analysis of the association between the serum levels of TNF-α and the activity of the disease (JADAS10 scores) in patients on therapy with adalimumab or etanercept in the total cohort of patients with JIA showed a weak negative correlation (Fig. 3) between the level of TNF-α and JADAS10 scores (p = 0.007), (r =  − 0.177).