IL1B and melanoma: Furthermore, moving among the 11 members of the large IL‐1 cytokine family, alongside the anti‐tumoral immunity suppressive role of IL‐38, also well investigated in melanoma, is the multilineage (both innate and adaptive) immunosuppressive role of IL‐1 through upregulation of Il‐37 in various lymphocyte subsets, notably in regulatory T (Treg) cells.12, 13