RPS19 and Diamond-Blackfan anemia: We have also shown in CD34+ cells from patients with RPS19-deficient DBA and treated or not with the PGK.CoRPS19LV that transduction with PGK.CoRPS19LV significantly increases the clonogenic potential of the erythroid progenitor cells (BFU-Es) (P ≤ 0.017) and improves the characteristic ineffective erythropoiesis from DBA.