There is a significant correlation between measures of cognitive tests, such as discrimination index in novel odor recognition test or escape latency in MWM with left ventricular ejection fraction, in type 2 diabetes mellitus (T2DM) stroke rodents that are treated with derived exosomes from human umbilical cord blood CD133+ cells (CD133 + Exo).117. This evidence concerns the gene PROM1 and diabetes mellitus.