EGFR and non-small cell lung carcinoma: Statistics show that there are at least 102 unique ex20ins variants in the US population,withD770_N771insSVD,V769_D770insASV,A763_Y764insFEQA,H773_V774insNPH, and D770_N771insG being the most common variants (16).The development of novel targeted therapies for NSCLC patients with EGFR ex20 mutations has made remarkable progress in recent years.