NFKB1 and familial dilated cardiomyopathy: Triptolide’s protective effects on cardiac tissue may be attributed to inhibiting the TLR4-induced NF-κB/IL-1β immune pathway, the NF-κB/TNF-α/VCAM-1-mediated inflammatory pathway, and downregulating TGF-β1/α-SMA/Vimentin involved in cardiac fibrosis, indicating potential beneficial effects of triptolide on DCM (93).