As shown in Figures 4B, E, the AUCs of IDH3A, BAX, MRPS6, GPT2, and risk score for AD diagnosis were, respectively, 0.991, 0.964, 0.986, 0.951, and 1.000, indicating that the efficiency of these 4 hub MitoDEGs and the model were good. Here, MRPS6 is linked to Alzheimer disease.