Furthermore, the proportion of MC04 with negligible AAL binding was more than doubled in SLE (1.7% vs. 0.7% in HC), whereas MC05 featuring the lowest Gal-1 binding and intermediate HLA-DR expression, was significantly more prevalent in SLE (9.2% vs. 3.8% in HC) (Figure 7F). This evidence concerns the gene LGALS1 and systemic lupus erythematosus.