NFE2L2 and asthma: Among the top five significant pathways identified in A549, the following were noteworthy: Pathogen Induced Cytokine Storm Signaling Pathway (p = 9.12E-4), Pulmonary Fibrosis Idiopathic Signaling Pathway (p = 7.94E-3), Airway Inflammation in Asthma (p = 1.6E-2), Nuclear factor erythroid 2-related factor 2 (NRF2)-mediated Oxidative Stress Response (p = 2.1E-2), and Mitochondrial Dysfunction (p = 2.7E-2).