CXCR6 and neoplasm: Evidence has shown that these cells can exhibit a pro-tumorigenic role, attributed to excessive production of certain cytokines associated with tumor progression (e.g., IL-8 in the case of MAIT) (Duan et al., 2019) or increased fibrogenesis (e.g., potentiated by iNKT-secreted CXCR6) (Wehr et al., 2013).