CRP and appendicitis: CRP level is a dynamic inflammation indicator well reflecting systemic inflammation elevating in response to inflammatory reactions, resistance to bacterial infections and tissue damage such as acute appendicitis (23), incarcerated groin hernia (10), intestinal obstruction (24), etc. As shown in our nomogram, CRP significantly contributed to intestinal necrosis, with higher CRP level greatly increasing the risk of intestinal necrosis and indicating the severity of the illness.