To further elucidate the link between PSMB1-10 genes expression and colorectal cancer we compared gene expression in different molecular subtypes of colorectal cancer from GSE39582 dataset (Marisa et al., 2013): tumors with BRAF, KRAS, or TP53 mutations, CpG island methylator phenotype (CIMP), DNA mismatch repair deficiency (MMR), or chromosomal instability (CIN). This evidence concerns the gene KRAS and cervical squamous intraepithelial neoplasia.