To further elucidate the link between PSMB1-10 genes expression and colorectal cancer we compared gene expression in different molecular subtypes of colorectal cancer from GSE39582 dataset (Marisa et al., 2013): tumors with BRAF, KRAS, or TP53 mutations, CpG island methylator phenotype (CIMP), DNA mismatch repair deficiency (MMR), or chromosomal instability (CIN). The gene discussed is PSMB1; the disease is cervical squamous intraepithelial neoplasia.