Through analysis, it was predicted that T1DM could be predicted from the high expression of 7 pivot genes: DNA Damage Inducible Transcript 4 (DDIT4), Establishment Of Sister Chromatid Cohesion N-Acetyltransferase 2 (ESCO2), SH3 Domain Binding Protein 4 (SH3BP4), Prickle Planar Cell Polarity Protein 1 (PRICKLE1), EPM2A Interacting Protein 1 (EPM2AIP1), Potassium Inwardly Rectifying Channel Subfamily J Member 15 (KCNJ15) and Glutamate Metabotropic Receptor 8 (GRM8). The gene discussed is PRICKLE1; the disease is type 1 diabetes mellitus.