C1QBP and cancer: Analysis using two deconvolution algorithms, Tumor Immune Estimation Resource (TIMER) and CIBERSORT 26, 27, with RNA-sequencing data from The Cancer Genome Atlas (TCGA), revealed high expression of C1QBP in macrophage, particularly in immunosuppressive M2-like macrophages among various cell types in the human breast cancer microenvironment (Figure 3A).