By analyzing 85 samples from the GSE33630 dataset, we found that POSTN and IL-4 were significantly up-regulated both in papillary thyroid cancer and anaplastic thyroid cancer tissues relative to normal thyroid tissues and POSTN levels were positively correlated with IL-4 in papillary thyroid cancer (Figure 7A-C). This evidence concerns the gene IL4 and thyroid gland papillary carcinoma.