Moreover, we found changes in expression levels of EMT indicators, such as upregulation of mesenchymal markers N-cadherin and Vimentin as well as downregulation of epithelial cell marker E-cadherin in OE-KRAS or siNF1 GBM cells, and these changes were reversed by OE-ERBIN (Figure 3C). This evidence concerns the gene ERBIN and glioblastoma.