Moreover, a direct comparison of the anti-AML effects of R428 and sdAb20-Fc at different molar concentrations (ranging from 10 nM to 10 μM) clearly demonstrated that R428 reduced the viability of both the KG-1a and THP-1 cell lines, regardless of their AXL expression, in a dose-dependent manner (Figure S7C-D). The gene discussed is AXL; the disease is acute myeloid leukemia.