IGHE and chronic rhinosinusitis with nasal polyps: However, the number of IgE-positive cells was still significantly greater in the eosinophil-dominant CRSwNP group than in the control group according to statistical analysis (p < 0.05; Fig. 2b), while the number of IgE-positive cells was significantly greater in the plasma cell-dominant CRSwNP group; thus, the p value between the control and plasma cell-dominant CRSwNP groups and between the eosinophil-dominant CRSwNP and plasma cell-dominant CRSwNP groups was less than 0.01 (Fig. 2b).