We demonstrated that decreased perioperative albumin levels (&Alb ≥ 4.55 g · L− 1) were an independent risk factor for CI-AKI and an important predictor of MACEs 1 year after PCI in patients with CHD; &Alb ≥ 4.55 g · L− 1 could not only be used for the early identification of CI-AKI in the short term after PCI in patients but also had high predictive value for MACEs 1 year after PCI. The gene discussed is ALB; the disease is acute kidney injury.