MYH11 and Patent ductus arteriosus: The most common manifestation caused by MYH11 variants was TAAD (41.18%, 42/102), followed by PDA (22.55%, 23/102), compound TAAD and PDA (TAAD + PDA) (9.80%, 10/102), and other vascular abnormalities (8.82%, 9/102) (Fig. 3).