The most 31 important genes including IL6, EGFR, STAT3, MMP9, CD44, FN1, CD4, TGFB1, CXCL8, CCL2, IL10, ICAM1, IL1A, CD274, KDR, SPP1, ITGB2, CDKN2A, PARP1, MYD88, AGT, NOTCH1, SERPINE1, TNFRSF1A, CDK1, CAV1, ITGB3, CDK4, FOXO3, MDM2, and PROM1, respectively, were considered as candidate biomarkers for GBM survival. The gene discussed is CD274; the disease is glioblastoma.