Through blocking the Warburg Effect through the PPARγ-Dependent WNT/β-catenin /Pyruvate Dehydrogenase Kinase Isozyme 1 Axis, PPARγ Coactivator-1 Suppresses Metastasis of Hepatocellular Carcinoma [45]. The gene discussed is PPARG; the disease is hepatocellular carcinoma.