Similarly, interactions were found for ERBB3, IL6R, and MMP12 in the AD-specific PPI network (S. Figure 9) and for ERBB3, ICAM1, IL1RL2, MANF, STAT6 and TNFSF8 in the AR-specific PPI network (S. Figure 10). Here, IL1RL2 is linked to Alzheimer disease.