In addition to the CCDC26 variant, analyzed families with brain tumors harbored GWAS variants, e.g. in the genes TERT, EGFR, CDKN2B-AS1, PHLDB1, and RTEL1 [variant frequency 0.23–0.80 (median 0.57) in the Finnish population] (Supplementary Table 8), which have been reported to confer a slightly increased risk of glioma26. This evidence concerns the gene TERT and brain neoplasm.