The KEGG analysis showed that these genes are enriched in pathways as small cell lung cancer, Proteoglycans in cancer, PI3K − Akt signaling pathway, Focal adhesion, Human cytomegalovirus infection, Kaposi sarcoma − associated herpesvirus infection, Bladder cancer, Colorectal cancer, Human papillomavirus infection (Fig. 5E, Supplement Table 7). This evidence concerns the gene AKT1 and Herpesviridae infectious disease.