To further elucidate the impact of Treg-mediated cGAS-STING suppression on MM cell tumorigenesis, the nude mice were injected with MM.1S cells, MM.1S cells with Tregs, MM.1S cells with Tregs and STING agonist-4, MM.1S cells with Tregs and IgG isotype or MM.1S cells with Tregs and TGF-β1 neutralizing antibody. The gene discussed is STING1; the disease is Miyoshi myopathy.