SAV1 and nasopharyngeal carcinoma: TL-SN exhibited IC50 values similar to SN in the treatment of most NPC cells and nearly 2 times the IC50 of SN in treating CNE-2 cells but the introduction of Lp-Sav improved treatment efficiency of TL-SN in all NPC cells, indicating a synergistic effect between Lp-Sav and TL-SN (Fig. 5k, l).