MAPK8 and alkaline phosphatase measurement: CoQ10 activation in AP mice reduces the levels of inflammatory factors and peroxides in pancreatic tissues, decreases the degree of leukocyte infiltration, and inhibits the expression of extracellular regulated protein kinase (ERK), which mediates the activation of the c-Jun N-terminal kinase (JNK) signaling pathway, thus alleviating the severity of AP [40].