TBP and cancer: As shown in Fig. 1A, our anti-TAF2 antibody was able to immunoprecipitate endogenous TAF2, as well as core subunits of the TFIID complex, including TBP, TAF4, TAF5, TAF6, and TAF7, in nuclear extracts from colorectal HCT116, embryonic kidney HEK-293, and ovarian A2780 cancer lines.