After screening, the clinical characteristics of patients with COVID-19-related encephalitis were compared with those of patients with confirmed herpes simplex virus type 1 encephalitis (HSV-1 encephalitis), human herpesvirus 3 encephalitis (HHV-3 encephalitis), NMDAR-antibody encephalitis, LGI1-antibody encephalitis, and GABAB-antibody encephalitis. This evidence concerns the gene LGI1 and viral encephalitis.