,8 The most widely occurring changes in glycosylation linked to cancer progression include an enhancement of N-glycan branching due to increased activity of the glycosyltransferase MGAT5,9 and alterations to α2-6 sialylated N-glycans - a modification driven by the sialyltransferase enzyme ST6GAL1.5 This evidence concerns the gene ST6GAL1 and cancer.