In contrast with the only previous study to investigate eosinophils in L. loa infection in a cross-sectional setting in a highly endemic, Central African population, [66], but in common with some previous reports from elsewhere (including endemic residents presenting at Western travel clinics) [67,68], we also found L. loa-infection to be associated to eosinophilia, eosinophil activation and to some extent circulating IL-5 levels. This evidence concerns the gene IL5 and Increased total eosinophil count.