When comparing the immunophenotypes of granulocytes from patients with different mutant genes in patients with ET or PMF, respectively, an immune antigen that was statistically different between patients with JAK2V617F-mutated PMF and patients with CALR-mutated PMF was not detected as well as a statistically different immunoantigen between patients with JAK2V617F-mutated ET and patients with CALR-mutated ET. The gene discussed is CALR; the disease is essential thrombocythemia.