The literature suggests that the pathogenesis and central toxicity progression of multiple neurodegenerative diseases are associated with abnormal levels of AChE and MAO (Patlolla A K, Tchounwou 2005; Huot and Fox S H, Brotchie 2016; Nasr and El-demerdash F M, El-nagar W 2016). Here, ACHE is linked to neurodegenerative disease.