Moreover, the cell surface proteoglycan glypican-1 (GPC-1) is also found in exosomes extracted from pancreatic and breast cancer patients (Lorenzon and Blandino, 2016; Wang et al., 2019b), which can also be detected in the early and late stages of pancreatic cancer compared to the serum of healthy controls. The gene discussed is GPC1; the disease is breast cancer.