NFKB1 and Hepatic fibrosis: Chlorogenic acid has been reported to protect against different types of liver fibrosis through NOX/ROS/MAPK, ERK/Nrf2, TLR4, and NF-κB pathways (Shi et al., 2013; Shi et al., 2016; Yuan et al., 2017; Wei et al., 2018).