CXCR4, CCR2, and CX3CR1 are chemokines that play a prominent role in breast cancer metastasis to the bone marrow and in the proliferation of tumor cells (Müller et al., 2001; Lu and Kang, 2009; Jamieson-Gladney et al., 2011). This evidence concerns the gene CXCR4 and neoplasm.