In the bone marrow, however, BMSCs produce chemoattractant proteins such as stromal cell-derived factor-1(SDF-1) and monocyte chemoattractant protein-1 (MCP-1) that attract DCTs and promote tumor growth and drug resistance in the microenvironment (Bergfeld and DeClerck, 2010). This evidence concerns the gene CXCL12 and neoplasm.