TERT and hepatocellular carcinoma: To further confirm the result, the cell viability assay was performed after BI2536 treatment in 13 cell lines with different histological and genetic background (Figure S1A), including two normal hepatocyte (THLE2 and THLE3), five HCC cells with TERT WT (MHCC‐97H, Huh1, SK‐HEP‐1, SNU761, PLC/PRC/5), six HCC cells with TERT Mut (HLF, SNU878, SNU886, SNU739, HLE, Huh7).