In experiments on mitochondrial transplantation in hepatocellular carcinoma, healthy mitochondria were found to inhibit tumor cells from undergoing glycolysis, promoted dephosphorylation of p-Bad, downregulated the expression of Bcl-2, increased Bax, and finally induced tumor cell apoptosis in a Caspase-dependent manner [95]. The gene discussed is BAD; the disease is neoplasm.