However, compared with uninfected controls, there were increased α-SMA, collagen I, and collagen IV positive areas around egg granulomas in the liver sections of Sj group (P < 0.0001, P < 0.001, and P < 0.001, respectively) and Sj + lact group (P < 0.001, P < 0.01, and P < 0.001, respectively). This evidence concerns the gene ACTA1 and Granuloma.