The results indicated that upregulation of LINC00330 expression in ESCC cells promoted the expression of the epithelial marker E-cadherin and reduced the expression of mesenchymal markers (Fibronectin, β-catenin, Vimentin, ZEB1, Snail, and N-cadherin; Fig. 2G&H, and Additional file 3: Figure S1L). This evidence concerns the gene VIM and esophageal squamous cell carcinoma.