We found that CCL2 was more highly expressed in ESCC tissues (Additional file 3: Figure S5A) and that its high expression was closely correlated with a higher stage grade (Additional file 3: Figure S5B) and poor prognostic survival (Additional file 3: Figure S5C, D), as opposed to LINC00330 (Fig. 1H, I). This evidence concerns the gene CCL2 and esophageal squamous cell carcinoma.