TRIM23 and colorectal carcinoma: Through immunohistochemistry (IHC) analysis of clinical samples of human CRC tissues and paired normal intestinal tissues, we found that the protein level of TRIM23 was slightly lower in CRC tissues (Fig. 8A; Appendix Fig. S2D), while there was no correlation between the protein level of TRIM23 and overall survival of patients (Appendix Fig. S2E).