CXCR1 and plasma cell myeloma: Based on data from Ng et al.34, where CXCR4 redirected CD38 CAR-expressing NK cells presented an enhanced BM homing in myeloma-carrying mice or where the co-expression of CXCR1 and the NKG2D CAR on NK cells was used to improve their efficacy against solid tumors9, one could expect this to at least be additive.