To determine whether I3P had the ability to promote AHR translocation in liver cancer cells, we measured the nuclear and cytosolic AHR fractions in HCC53N cells 1 h after incubation with I3P (Fig. 8m) and found that I3P efficiently drove nuclear translocation of AHR but had no effect of MYC levels or localization. This evidence concerns the gene AHR and liver cancer.