FB1, as a toxic stimulate factor, can trigger abnormal expression of TNF-α and inflammatory factors, including IL-1β (Interleukin-1 bata), IL-2 (Interleukin-2), IL-4 (Interleukin-4), and IL-10 (Interleukin-10), and cause intestinal inflammation in mice (Li et al. 2020). Here, IL4 is linked to inflammation.