YME1L1 and glioma: A previous study demonstrated the crucial role of YME1L within glioma cells in facilitating the transcription and expression of G protein subunit alpha i1 (Gαi1) [27], a key protein essential for the activation of Akt-mTOR cascade through various receptor tyrosine kinases (RTKs) and non-RTK receptors [38, 39, 44–51].