PDGFRβ+ fibroblasts co-expressing PDGFRα, which are essentially associated with the large pial penetrating vasculature, and PDGFRβ+ pericytes, which are essentially associated with parenchymal microvasculature, both have been reported to contribute to fibrotic scar formation after ischemic stroke [56, 92]. This evidence concerns the gene PDGFRA and ischemic stroke.