Drug discovery analysis followed by network pharmacology analysis identified some important phytoconstituents germichrysone, benzeneacetic acid, Flavan-3-ol, 5,7,3',4'-Tetrahydroxy-6, 8-dimethoxyflavon, dihydrokaempferol, and epiafzelechin which revealed that these were the main constituents related to hypertension targets while TLR4, MMP9, MAPK14, AKT1, VEGFA and HSP90AA1 were the main hypertension-related molecular targets. The gene discussed is TLR4; the disease is Hypertension.