In summary, we demonstrated in this study, using a cellular model based on the LX-2 cells, that the hsa_circ_0009096, which is highly expressed in hepatic tissues of patients with BA, could fundamentally promote HSC proliferation, activation, and hepatic fibrosis, through the sponging of miR-370-3p to modulate TGFBR2 expression and the TGF-β1 signaling pathway. Here, TGFB1 is linked to breast angiosarcoma.